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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPCN2
All Species:
12.12
Human Site:
Y432
Identified Species:
26.67
UniProt:
Q8NHX9
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NHX9
NP_620714.2
752
85243
Y432
A
Q
F
L
F
G
H
Y
Y
F
D
Y
L
G
N
Chimpanzee
Pan troglodytes
XP_001173935
763
85554
Y443
A
Q
F
L
F
G
H
Y
Y
F
D
Y
L
G
N
Rhesus Macaque
Macaca mulatta
XP_001101571
752
85154
Y432
A
Q
F
V
F
G
H
Y
Y
F
D
Y
L
G
N
Dog
Lupus familis
XP_540804
876
99392
R556
A
Q
F
L
F
S
H
R
Y
F
D
Y
L
G
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWC0
731
83577
H416
A
Q
F
I
F
S
H
H
Y
F
D
Y
L
G
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506335
738
85478
R418
A
Q
L
I
I
S
H
R
Y
F
N
Y
L
G
N
Chicken
Gallus gallus
NP_001137403
752
87078
V390
V
V
R
H
R
G
F
V
W
T
Y
D
V
I
I
Frog
Xenopus laevis
NP_001089672
327
37780
L52
A
I
N
C
F
F
I
L
Y
Y
V
L
E
M
G
Zebra Danio
Brachydanio rerio
A0JMD4
774
89166
Y448
I
Q
Y
V
Y
S
H
Y
Y
I
S
V
L
G
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001138448
798
92257
R481
L
Q
S
C
I
V
H
R
F
F
G
Y
C
G
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94KI8
733
84855
I414
L
F
E
H
F
P
Q
I
Y
H
S
A
L
S
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.5
95.3
71.1
N.A.
72.8
N.A.
N.A.
69.5
28.1
29.2
54.6
N.A.
N.A.
N.A.
N.A.
42.4
Protein Similarity:
100
92.4
96.9
77
N.A.
84.7
N.A.
N.A.
82.3
48.9
36.2
72.2
N.A.
N.A.
N.A.
N.A.
60.4
P-Site Identity:
100
100
93.3
86.6
N.A.
80
N.A.
N.A.
60
6.6
20
46.6
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
N.A.
N.A.
73.3
20
26.6
66.6
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
64
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
19
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
46
10
0
0
0
% D
% Glu:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% E
% Phe:
0
10
46
0
64
10
10
0
10
64
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
37
0
0
0
0
10
0
0
73
10
% G
% His:
0
0
0
19
0
0
73
10
0
10
0
0
0
0
0
% H
% Ile:
10
10
0
19
19
0
10
10
0
10
0
0
0
10
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
19
0
10
28
0
0
0
10
0
0
0
10
73
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
64
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
73
0
0
0
0
10
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
10
0
10
0
0
28
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
0
37
0
0
0
0
19
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% T
% Val:
10
10
0
19
0
10
0
10
0
0
10
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
10
0
0
37
82
10
10
64
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _